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Allele : Cdh4<tm1Semb> cadherin 4; targeted mutation 1, Henrik Semb

Primary Identifier  MGI:2180782 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdh4
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a neomycin selection cassette replaced exon 1 and exon 2. An absence of transcript in kidneys isolated from homozygous mutant embryos was determined via Northern blot analysis using probes for the 5' terminal, middle, and 3' terminal of the endogenous cDNA. Immunoblotting of brain extracts showed a lack of protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • R-cadherin<->,
  • R-cadherin<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories