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Allele : Creb1<tm2Gsc> cAMP responsive element binding protein 1; targeted mutation 2, Gunther Schutz

Primary Identifier  MGI:2181382 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Creb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A promoterless neomycin resistance gene was inserted in frame into exon 10, and all of intron 10 and part of exon 11 were deleted. The deleted sequences encode part of the DNA binding domain and the leucine zipper domain. RT-PCR analysis on total brain RNA demonstrated that no transcripts containing the 3' end were detectable; however, a fusion transcript containing the lacZ sequences is detected.
  • mutations:
  • Insertion
  • synonyms:
  • CREB -,
  • CREB -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

9 Publication categories