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Allele : Ccnd1<tm1Dsn> cyclin D1; targeted mutation 1, Clive Dickson

Primary Identifier  MGI:2180640 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccnd1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a PGK-neo cassette deleted 200 nucleotides of exon 1 encoding a portion of the LXCXE motif. Northern blot analysis revealed an absence of transcript in homozygous mutant mice. Protein expression was not detected by Western blot analyses of extracts from homozygous mutant kidney, lung, and seminal vesicle tissue.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • cyclin D1<->,
  • cyclin D1<->,
  • Ccnd1(-),
  • Ccnd1(-),
  • Cyl-1<->,
  • Cyl-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

18 Publication categories