Primary Identifier | MGI:2180680 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd22 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Portions of exons 3 and 4 were replaced with a neomycin selection cassette, which introduced stop codons into all three reading frames. The deleted region encoded the translational start site, leader sequence, and the ligand-binding immunoglobulin domain 1. The splice sites on the 5' and 3' terminals of exons 3 and 4, respectively, were left intact. |