Primary Identifier | MGI:2180841 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cebpd |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
description | mRNA expression of Slc5a8 and Slc5a12 is undetectable in the kidneys of these mice, although expression appears normal in non-renal tissues (J:116932). |
molecularNote | The single exon containing the entire coding region was replaced by a neomycin selection cassette. An absence of transcript in kidney and hippocampal tissue isolated from homozygous mutant mice was determined by Northern blot analysis. |