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Allele : Irx4<tm1Jse> Iroquois homeobox 4; targeted mutation 1, Jonathon G Seidman

Primary Identifier  MGI:2180895 Allele Type  Targeted
Attribute String  Null/knockout Gene  Irx4
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neo construct replaced exon 2 and a portion of exon 3. The targeted allele was shown to produce two truncated transcripts via Northern blot and RT-PCR analyses. Further RT-PCR analysis using various probes showed that the aberrant transcripts lacked the essential ribosome binding domain as well as the initiation codon.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Irx4<deltaex2>,
  • Irx4<deltaex2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories