| Primary Identifier | MGI:2181227 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tnfrsf11b |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a 1.3 kb PGK-neo cassette into exon 2 via homologous recombination. The insertion results in disruption of the cysteine-rich domains, which are involved in the biological activity of the protein. Homozygous mutant animals lacked gene transcription and protein product as determined by Northern and Western blot analyses. |
