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Allele : Ppp3cb<tm1Jmk> protein phosphatase 3, catalytic subunit, beta isoform; targeted mutation 1, Jeffery D Molkentin
Primary Identifier  MGI:2181294 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ppp3cb
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The exon encoding the catalytic domain of the protein was replaced with a neomycin resistance cassette via homologous recombination. Western blot analysis confirmed the absence of gene expression in brain of homozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CnAbeta KO,
  • Abeta-,
  • Abeta-,
  • CnAbeta-,
  • Cnab<->,
  • Cnab<->,
  • CnAbeta-,
  • CnAbeta KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

37 Publication categories





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