| First Author | Barlow C | Year | 1997 |
| Journal | Nucleic Acids Res | Volume | 25 |
| Issue | 12 | Pages | 2543-5 |
| PubMed ID | 9171115 | Mgi Jnum | J:67907 |
| Mgi Id | MGI:1931680 | Doi | 10.1093/nar/25.12.2543 |
| Citation | Barlow C, et al. (1997) Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments. Nucleic Acids Res 25(12):2543-5 |
| abstractText | Functional analysis of mammalian genes relies, in part, on targeted mutations generated by homologous recombination in mice. We have developed a strategy for adipose-specific inactivation of loxP-floxed gene segments. Transgenic mice have been established that express Cre recombinase under the control of the adipose-specific aP2 enhancer/promoter. Crossing of the aP2/ Cre mice with any loxP-floxed gene will facilitate its functional analysis in adipose tissue. |
