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Allele : Ireb2<tm1Roua> iron responsive element binding protein 2; targeted mutation 1, Tracey Rouault

Primary Identifier  MGI:2181660 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ireb2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a neomycin cassette deleted portions of exon 3 and 4. Northern blot analysis showed the presence of a larger transcript, containing the neomycin gene, in homozygous mutant mice. A lack of Ireb2 protein and normal levels of Ireb1 was determined by Western blot analysis of fibroblast lysates derived from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IRP-2-,
  • IRP2-,
  • Ireb2-,
  • IRP-2-,
  • Ireb2-,
  • IRP2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

33 Publication categories

Trail: Allele