Primary Identifier | MGI:2181660 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ireb2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The insertion of a neomycin cassette deleted portions of exon 3 and 4. Northern blot analysis showed the presence of a larger transcript, containing the neomycin gene, in homozygous mutant mice. A lack of Ireb2 protein and normal levels of Ireb1 was determined by Western blot analysis of fibroblast lysates derived from homozygous mutant mice. |