| Primary Identifier | MGI:2180798 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cd9 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2, which encodes the first transmembrane domain, was replaced with a neomycin resistance gene. Sequenc analysis of a transcript present in mutant mice showed that exon 1 had spliced to exon 3 causing a frameshift mutation that introduced a stop codon in exon 3. While a cytoplasmic domain may have been produced, flow cytometric analysis of bone marrow macrophages showed no cell surface protein expression. |
