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Allele : Cd7<tm1Bfh> CD7 antigen; targeted mutation 1, Barton F Haynes

Primary Identifier  MGI:2180804 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd7
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was disrupted by the introduction of a stop codon upstream of sequence encoding the transmembrane domain. A PGK-neo cassette was inserted just downstream of the introduced stop codon. Northern blot analysis of thymocytes and splenocytes showed a lack of protein expression in homozygous mutant mice. These results were confirmed by RT-PCR analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CD7-,
  • CD7-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories