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Allele : Egr1<tm1Pch> early growth response 1; targeted mutation 1, Patrick Charnay

Primary Identifier  MGI:2181755 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Egr1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A construct containing a promoterless lacZ gene adjoined to a neomycin selection gene was inserted 50 bp upstream of the translational start codon. The insertion introduced a frameshift mutation upstream of the DNA-binding domain. An absence of encoded mRNA and protein was determined by in situ hybridization and immunocytochemical analyses of homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • Krox-24-,
  • Zif268-,
  • Krox-24-,
  • Egr-1<-LacZ)>,
  • Zif268-,
  • Egr-1<-LacZ)>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

25 Publication categories