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Allele : Ins2<tm1Jja> insulin II; targeted mutation 1, Jacques Jami

Primary Identifier	MGI:2181878	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Ins2
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

The majority of the coding region was replaced by the insertion of a lacZ-neo fusion gene. The expression of lacZ was found to be under the control of the endogenous promoter via cytochemical assays.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Ins2-,
proinsulin 2-,
proins-2-,
proins-2-,
proinsulin 2-,
Ins2-

earliestPublication:
Duvillie B, et al. (1997) Phenotypic alterations in insulin-deficient mutant mice. Proc Natl Acad Sci U S A 94(10):5137-40

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

10 Carried By

0 Driven By

49 Publication categories

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