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Allele : Sp3<tm1Sus> trans-acting transcription factor 3; targeted mutation 1, Guntram Suske

Primary Identifier  MGI:2182438 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sp3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2, which encodes the glutamine-rich activation domain, was replaced with a cassette containing an IRES-lacZ-neo fusion gene, adjoined to a splice acceptor site. The three isoforms produced from the endogenous allele were undetected in homozygous mutant mice by Western blot analysis of nuclear extracts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Sp3-,
  • Sp3-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

13 Publication categories