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Allele : Dnmt1<tm1Pwl> DNA methyltransferase 1; targeted mutation 1, Peter W Laird

Primary Identifier  MGI:2182453 Allele Type  Targeted
Attribute String  Hypomorph Gene  Dnmt1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A hypomorphic allele was generated by the insertion of the operater sequence (lacO) from the lac operon in intron 3 via recombinatory techniques. Quantitation of Northern blot analysis results showed a 40% reduction in transcript levels versus wild-type.
  • mutations:
  • Insertion
  • synonyms:
  • Dnmt<R>,
  • Dnmt1<R>,
  • Dnmt<R>,
  • Dnmt1<R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories