Primary Identifier | MGI:2182467 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kcnj10 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The coding exon of the gene encoding amino acids 33-266, which includes part of the C-terminus and putative transmembrane domains, was replaced with a PGK-neo cassette via homologous recombination. Northern blot analysis of retinas from homozygous mutant animals did not detect gene expression. |