Primary Identifier | MGI:2181695 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd9 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence, encompassing a portion of exon 3 and all of exon 4 and encoding the second and third transmembrane domains, was replaced with a neomycin selection cassette. Flow cytometric analysis showed an absence of encoded protein on the surface of bone marrow cells obtained from homozygous mutant mice. An absence of protein expression on homozygous mutant oocyte plasma membranes was determined via immunofluorescent staining. |