Primary Identifier | MGI:2181791 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plec |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 31, encoding the entire central rod domain, was replaced by a neomycin selection cassette. Transcript was undetected by RT-PCR analysis of samples derived from homozygous mutant skin and muscle tissue. An absence of protein was determined by immunoblot analysis of skin and muscle tissue derived from homozygous mutant mice. |