Primary Identifier | MGI:2181792 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plec |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 through 4 were replaced by a neomycin selection cassette. The 5' end of exon 2 serves as a splice-acceptor site utilized in all four identified alternative transcripts. Transcript was undetected by RT-PCR analysis of samples derived from homozygous mutant skin and muscle tissue. An absence of protein was determined by immunoblot analysis of skin and muscle tissue derived from homozygous mutant mice. |