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Allele : Plec<tm2Gwi> plectin; targeted mutation 2, Gerhard Wiche

Primary Identifier  MGI:2181792 Allele Type  Targeted
Attribute String  Null/knockout Gene  Plec
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 through 4 were replaced by a neomycin selection cassette. The 5' end of exon 2 serves as a splice-acceptor site utilized in all four identified alternative transcripts. Transcript was undetected by RT-PCR analysis of samples derived from homozygous mutant skin and muscle tissue. An absence of protein was determined by immunoblot analysis of skin and muscle tissue derived from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • exon 2-4-deficient,
  • exon 2-4-deficient
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories