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Allele : Atxn1<tm2Hzo> ataxin 1; targeted mutation 2, Huda Y Zoghbi

Primary Identifier  MGI:2181805 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atxn1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 8 was replaced with a PGK-hprt cassette via homologous recombination resulting in the deletion of amino acids 1-616. Western blot analysis of brain extracts from homozygous mutant animals using an antibody directed against the C-terminus of the protein did not detect protein expression thus verifying the null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Atxn1<tm1Zuk>,
  • Atxn1<tm1Zuk>,
  • Sca1<m1>,
  • Sca1<->,
  • Sca1<->,
  • Sca1<m1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

23 Publication categories