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Allele : Rho<tm1Phm> rhodopsin; targeted mutation 1, Peter Humphries

Primary Identifier  MGI:2181812 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rho
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette under the control of a polymerase II promoter was inserted at codon 135 in exon 2. RT-PCR analysis of total RNA derived from ocular tissue showed an absence of transcript in homozygous mutant mice. A lack of encoded protein was determined in homozygous mutant mice via immunocytochemical staining of retinal sections.
  • mutations:
  • Insertion
  • synonyms:
  • R<->,
  • R<->,
  • Rho-,
  • Rho-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

81 Publication categories