| Primary Identifier | MGI:2181950 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Del(3Cd1d2-Cd1d1)1Crw |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cd1d1 and Cd1d2 are adjacent loci that are arranged tail-to-tail, enabling the deletion of exons 4 through 6 from both loci with the insertion of a single neomycin selection cassette. RT-PCR analysis showed an absence of transcript in all tissues tested from homozygous mutant mice. A lack of protein surface expression was determined by immunofluorescence of thymocytes and splenocytes from homozygous mutant animals. |
