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Allele : Ctss<tm1Eae> cathepsin S; targeted mutation 1, Eileen A Elliot
Primary Identifier  MGI:2182132 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ctss
Transmission  Germline Strain of Origin  DBA/1LacJ
Is Recombinase  false Is Wild Type  false
description  The author (Renee LeBoeuf) has confirmed that the allele used in the reference J:153355 was incorrectly reported as Ctsstm1Hap; the correct allele is Ctsstm1Eae .
molecularNote  A neomycin selection cassette replaced a 3.0kb region containing the active site residue. Functional ablation of the protein product in homozygous mutant mice was determined via an active-site labeling assay of splenocytes and LPS B cell blasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • catS<->,
  • catS<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Carried By

Trail: Allele

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Trail: Allele




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