Primary Identifier | MGI:2182133 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ctss |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 5, encoding the active site cysteine, was replaced with a neomycin selection cassette. Western blot analysis showed an absence of encoded protein in splenocyte and dendritic cell lysates derived from homozygous mutant mice. |