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Allele : Hmbs<tm1Uam> hydroxymethylbilane synthase; targeted mutation 1, Urs A Meyer

Primary Identifier  MGI:2182340 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hmbs
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A promoterless neomycin selection cassette was inserted into exon 3, which is common to all isoforms. Hepatic enzymatic activity, the conversion of porphobilinogen to uroporphyrin, was reduced by approximately 50% in heterozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • T3,
  • T3
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories