| Primary Identifier | MGI:2182340 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hmbs |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A promoterless neomycin selection cassette was inserted into exon 3, which is common to all isoforms. Hepatic enzymatic activity, the conversion of porphobilinogen to uroporphyrin, was reduced by approximately 50% in heterozygous mice. |