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Allele : F7<tm1Pec> coagulation factor VII; targeted mutation 1, Peter Carmeliet

Primary Identifier  MGI:2182766 Allele Type  Targeted
Attribute String  Null/knockout Gene  F7
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region for the mature protein, contained by exons 2 through 8, was replaced with a neomycin selection cassette. Northern blot analysis of total hepatic RNA showed an absence of transcript in homozygous mutant mice. An assay of procoagulation detected no such activity in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • FVII-,
  • FVII-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories