Primary Identifier | MGI:2182789 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ets1 |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A region encompassing all of exon 3 and a portion of exon 4 was deleted by the insertion of a neomycin selection cassette. Encoded protein was undetected via immunoblot analysis of protein extracts from homozygous mutant thymocytes. Subsequent western blot analysis has determined that 1% to 5% of endogenous levels of a protein lacking the Point domain is expressed. |