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Allele : Map2k4<tm1Flv> mitogen-activated protein kinase kinase 4; targeted mutation 1, Richard A Flavell

Primary Identifier  MGI:2183040 Allele Type  Targeted
Attribute String  Null/knockout Gene  Map2k4
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3.5 kb fragment containg coding sequences for amino acids 211-268 was replaced with a neomycin selection cassette. These sequences include essential phosphorylation sites for protein activation. Western blot analysis on homozygous ES cells demonstrated that no detectable protein was made from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MKK4 -,
  • MKK4 -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories