| Primary Identifier | MGI:2182080 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mesp1 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| description | Chimera analysis in which double homozygous Mesp1tm3Ysa and Mesp2tm3(cre)Ysa mutant embryos were aggregated with wild-type embryos show that embryos develop normally, however double knock-out cells are scarcely seen in the anterior-cephalic and heart mesoderm, but they do contribute to the formation of somites, notochord, and gut, and the atrial appendage is exclusively composed of the mutant cells (J:62984). |
| molecularNote | Exons 1 and 2 were disrupted by the insertion of a PGK-neo cassette. |
