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Allele : Lta/Tnf<tm1Eug> tumor necrosis factor; targeted mutation 1, Hans-Pietro Eugster

Primary Identifier	MGI:2182273	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Tnf
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	false	Is Wild Type	false

molecularNote

The insertion of a single neomycin selection cassette deleted exons 2 and 3 of the Lta locus and exon 1 through the middle of exon 4 of the Tnf locus.

mutations:
Insertion,
Intergenic deletion

cellLines:
Not Specified

synonyms:
tnf/ltatm1,
TNF/LTalpha-,
tnf/ltatm1,
TNF-LTalpha-,
TNF/LTalpha-,
TNF-LTalpha-

earliestPublication:
Eugster HP, et al. (1996) Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. Int Immunol 8(1):23-36

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

38 Publication categories

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