Primary Identifier | MGI:2182408 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Dnmt3a |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 0.3kb region encoding the PC and ENV motifs was replaced with a cassette containing an IRES-lacZ gene and a neo gene. Northern blot analysis of total RNA showed an absence of transcript in homozygous mutant mice. X-gal staining of heterozygous embryos revealed expression of beta-galactosidase. |