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Allele : Dnmt3a<tm1Enl> DNA methyltransferase 3A; targeted mutation 1, En Li

Primary Identifier  MGI:2182408 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Dnmt3a
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A 0.3kb region encoding the PC and ENV motifs was replaced with a cassette containing an IRES-lacZ gene and a neo gene. Northern blot analysis of total RNA showed an absence of transcript in homozygous mutant mice. X-gal staining of heterozygous embryos revealed expression of beta-galactosidase.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories