Primary Identifier | MGI:2182409 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Dnmt3b |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.4kb region encoding the PC and ENV motifs was replaced with a cassette containing IRES-lacZ and neo. Northern blot analysis of total RNA showed transcript levels to be reduced in heterozygous mice. X-gal staining of heterozygous embryos revealed expression of beta-galactosidase. |