| Primary Identifier | MGI:2182608 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Plpp2 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequence encoding the amino acids 47 through 160 was replaced by a neomycin selection cassette inserted by homologous recombination. The deleted region encompassed the second and third transmembrane domains as well as the first domain of the conserved phosphatase superfamily motifs. Northern blot analysis demonstrated an absence of transcript in homozygous mutant mice. |
