Primary Identifier | MGI:2182612 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Krt5 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The promoter and first 2 exons were replaced with an Hprt cassette via homologous recombination. Northern blot of homozygous mutant animals showed complete absence of gene expression. Western blot analysis of skin protein extracts from homozygous mutants showed lack of protein expression. |