| Primary Identifier | MGI:2182618 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hdc |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A portion of the gene from intron 5 to exon 9 was replaced with a PGK-neo cassette via homologous recombination resulting in the deletion of the coenzyme binding site encoded by exon 8. Northern blot analysis of kidneys from homozygous mutant animals verified the absence of gene expression. |
