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Allele : Ezh2<tm1Jnw> enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1, Thomas Jenuwein

Primary Identifier  MGI:2182844 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ezh2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 5 and 6 were disrupted by the insertion of a cassette containing lacZ and neo, preventing the transcription of sequence encoding domain II and the carboxy terminal SET domain. Transcript was undetected in homozygous mutant embryos via in situ hybridization. Beta-galactosidase expression was not detected.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories