Primary Identifier | MGI:2183212 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gucy2e |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced the 3' portion of exon 5 encoding the transmembrane domain. Western blot analysis of protein extracts obtained from eyecups showed an absence of encoded protein in homozygous mice. |