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Allele : Gucy2e<tm1Gar> guanylate cyclase 2e; targeted mutation 1, David L Garbers

Primary Identifier  MGI:2183212 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gucy2e
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced the 3' portion of exon 5 encoding the transmembrane domain. Western blot analysis of protein extracts obtained from eyecups showed an absence of encoded protein in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GC-E -,
  • GC-E -,
  • GC1 KO,
  • GC1 KO,
  • RetGC1<->,
  • RetGC1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

29 Publication categories