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Allele : Pten<tm1Mro> phosphatase and tensin homolog; targeted mutation 1, Silvia Marino

Primary Identifier  MGI:2183284 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Pten
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector which contained a floxed neomycin selection cassette in intron 4 and a loxP site in intron 5 was electroporated into ES cells that were subsequently transiently transfected with a cre recombinase expression plasmid. The expression of cre resulted in the excision of the neo transgene, leaving exon 5 flanked by loxP sites. Mice carrying this allele were used to generate Ptentm1.1.
  • mutations:
  • Insertion
  • synonyms:
  • Pten<fx>,
  • Pten<LoxP>,
  • Pten<fx>,
  • Pten<flox>,
  • Pten<fl>,
  • Pten<fl>,
  • Pten<LoxP>,
  • Pten<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

44 Publication categories