| Primary Identifier | MGI:2182559 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gphn |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette replaced exon 1 and upstream regulatory sequence. Northern blot analysis of total RNA obtained from brain tissue showed an absence of transcript in homozygous mutant mice. A lack of encoded protein was determined via Western blot analysis of protein extracts from the brain. Protein was undetected by staining of spinal cord sections from homozygous mutant mice. |
