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Allele : Fkbp1b<tm1Syf> FK506 binding protein 1b; targeted mutation 1, Sidney Fleischer

Primary Identifier  MGI:2182644 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fkbp1b
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3, which encodes binding sites for Ryr2, FK506, and calcineurin, was replaced with a PGK-neo cassette via homologous recombination. Gene expression was absent in hearts from homozygous mutant animals as demonstrated by RT-PCR analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • FKBP12.6<->,
  • FKBP12.6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

18 Publication categories