| Primary Identifier | MGI:2182862 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Hip1 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 13.7 kb region spanning from exon 2 to exon 7 was replaced with a loxP-flanked neomycin resistance cassette via homologous recombination. Absence of gene expression was verified in brain and testicular extracts of homozygous mutant animals by Western blot analysis using a monoclonal antibody directed against a portion of the protein deleted by the gene targeting event. Phenotypic analysis in J:90400 suggests that this allele may be a hypomorph. |
