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Allele : Cnr1<tm1.1Ltz> cannabinoid receptor 1; targeted mutation 1.1, Beat Lutz

Primary Identifier  MGI:2182924 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cnr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was generated by breeding mice heterozygous for Cnr1tm1Ltz with transgenic mice ubiquitously expressing cre recombinase. Southern blot analysis showed that the entire open reading frame was removed, leaving a single loxP site and the FLP-recombinase target (FRT) flanked neo transgene in the single exon at this locus. A lack of transcript was determined via in situ hybridization of homozygous mutant embyros.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CB1-,
  • CB1R<->,
  • CB1R<->,
  • CB1<null>,
  • CB1-,
  • CB1<null>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

99 Publication categories

Trail: Allele