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Allele : Mtf1<tm1Wsc> metal response element binding transcription factor 1; targeted mutation 1, Walter Schaffner

Primary Identifier  MGI:2182939 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mtf1
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced sequences encoding the first two and a portion of the third zinc-finger domain. RT-PCR analysis of RNA from mutant embryos revealed the presence of an amino-terminal fragment, truncating 39 base pairs downstream of the 5' insertion point. The truncated transcript lacks sequence encoding 3 zinc-finger domains and the acidic, proline-rich, and serine/threonine-rich regions.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MTF-1<->,
  • MTF-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories