| Primary Identifier | MGI:2183167 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Gabra3 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A point mutation was introduced into codon 126 (exon 4) resulting in the substitution of histidine with arginine (H126R). The targeting vector also contained a floxed neomycin cassette in intron 3 for selection. A silent mutation was introduced at codon 150, generating a novel KpnI site. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Gabra3tm1.1Uru. |
