| First Author | Földy C | Year | 2010 |
| Journal | Nat Neurosci | Volume | 13 |
| Issue | 9 | Pages | 1047-9 |
| PubMed ID | 20676104 | Mgi Jnum | J:165351 |
| Mgi Id | MGI:4837041 | Doi | 10.1038/nn.2609 |
| Citation | Foldy C, et al. (2010) Regulation of fast-spiking basket cell synapses by the chloride channel ClC-2. Nat Neurosci 13(9):1047-9 |
| abstractText | Parvalbumin-expressing, fast-spiking basket cells are important for the generation of synchronous, rhythmic population activities in the hippocampus. We found that GABAA receptor-mediated synaptic inputs from murine parvalbumin-expressing basket cells were selectively modulated by the membrane voltage- and intracellular chloride-dependent chloride channel ClC-2. Our data reveal a previously unknown cell type-specific regulation of intracellular chloride homeostasis in the perisomatic region of hippocampal pyramidal neurons. |
