|  Help  |  About  |  Contact Us

Allele : Mdm4<tm1Glo> transformed mouse 3T3 cell double minute 4; targeted mutation 1, Guillermina Lozano

Primary Identifier  MGI:2183485 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mdm4
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 through 5 were replaced with a neomycin selection cassette. The deleted region encoded the majority of the Trp53-binding domain (amino acids 27-96). Aberrant splicing around the neo transgene would result in a frameshift mutation. Protein was undetected in homozygous mutant mice by Western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mdm4<->,
  • Mdm4<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories

Trail: Allele