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Allele : Tg(Prnp-ATXN7*92Q)6076Als transgene insertion 6076, Albert R La Spada
Primary Identifier  MGI:2183508 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Prnp-ATXN7*92Q)6076Als
Inheritance Mode  Not Specified Strain of Origin  (C57BL/6J x C3H/HeJ)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The coding region of human SCA7, containing 92 CAG repeats, was inserted into a murine prion protein promoter (MoPrP) construct. Expression was targeted to the outer nuclear layer, the inner nuclear layer, and the ganglion cell layer of the retina. Two lines (6076-92Q and 6561-92Q) were made.
  • mutations:
  • Insertion
  • synonyms:
  • PrP-SCA7-c92Q,
  • ATXN-92Q,
  • Tg(SCA7)c92QAls,
  • ATXN-92Q,
  • PrP-SCA7-c92Q,
  • Tg(SCA7)c92QAls
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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