| Primary Identifier | MGI:2183737 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sftpa1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Portions of exons 3 and 4 (base pairs 795 through 1049) were deleted by the insertion of a PGK-neo cassette. Northern blot analysis of RNA obtained from lung tissue showed an absence of transcript in homozygous mutant mice. The lack of encoded protein was confirmed by Western blot analysis of lung homogenates and immunohistochemical staining of alveolar type II cells. |
